Summary from:
Chance, F. S., Nelson, S. B., and Abbott, L. F. (1998) Temporal Characteristics
of V1 Cells Arising from Synaptic Depression. Bower, J. ed. Computational
Neuroscience Trends in Research, 1998 (Plenum, NY).
Synaptic depression provides a possible mechanism for nonlinear dynamics
in V1 simple cell responses. A model V1 simple cell with synaptic depression
on its afferent synapses has a realistic temporal frequency response curve
with enhanced responses to transient high-frequency stimuli. Correlation
between the amount of depression and the location of afferent receptive fields
can give rise to direction selectivity. The direction selective model constructed
in this way demonstrates direction selectivity over a range of stimulus
contrasts and temporal frequencies similar to those in experimental data.
Model membrane potential fluctuations in response to stationary gratings
closely resemble those of intracellular recordings. Finally, a slower component
of depression can reproduce effects seen in contrast adaptation experiments.
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